The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

In a serendipitous discovery, UC San Diego researchers using cryo-EM technology captured the first visualizations of the 3-D structure of the muscle acetylcholine receptor in fetal and adult muscles.

“This article illuminates the biology behind EDG-5506, demonstrating that modulation of fast skeletal muscle contraction protects against muscle injury, degeneration and fibrosis in models of DMD,” ...

The findings could have implications for robotics, prosthetics and energy efficient machines. John McGrath and José Alvarado with HillBot, a robot designed to test parameters of muscle strength and ...

Transverse tubules (T-tubules) play a significant role in muscle contraction. However, the underlying mechanism of their ...