Published in the journal Blood, the research focuses on finding smarter ways to treat myelofibrosis by targeting the abnormal blood cells that drive the disease using immunotherapy, rather than just ...
编者按:今年以来,siRNA疗法在治疗凝血相关疾病的研究方面取得了重要里程碑进展。RNA干扰(RNAi)机制通过在肝脏细胞中沉默编码凝血因子或天然抗凝物的mRNA,为治疗凝血相关疾病提供了一种全新的治疗模式。基于GalNAc偶联的递送技术,是将治疗性siRNA分子高效递送到肝脏的关键之一。药明康德旗下WuXi ...