provides a genome-wide query coverage metric (qcovGnm), which enables accurate interpretation of search results - particularly for circular queries (such as plasmid, virus, and mtDNA) against both ...

Introduction: Medullary thyroid carcinoma is a rare cancer that originates in parafollicular C cells and can be sporadic or hereditary. Both sporadic and hereditary diseases are primarily caused by ...

The reliability of multiple sequence alignment (MSA) results directly determines the credibility of the conclusions drawn from biological research. However, MSA is inherently an NP-hard problem, ...

Abstract: Sequence alignment is a fundamental step in genomic data analysis. Third-generation sequencing technology facilitates the acquisition of high-quality genomic data but the explosive growth of ...

Introdction: The CD300 family comprises immunoglobulin superfamily receptors that regulate immune cell function through inhibitory or activating signals. CD300A and CD300C form a paired receptor ...

Mr. O’Neal, a correspondent for The Economist, will be in charge of championing “personal liberties and free markets,” the section’s new direction laid out by Jeff Bezos. By Benjamin Mullin The ...

Current methods of assessing the similarity between proteins are based on protein sequence alignment. However, alignment is ineffective for intrinsically disordered regions (IDRs) given their rapid ...

Abstract: Sequence alignment is a method of positioning two (Pairwise Alignment) or more (Multiple Sequence Alignment) biological sequences of characters (such as DNA, RNA, or Protein sequences) in ...