Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

ABSTRACT: DNA, deoxyribonucleic acid, carrying encoded genetic information at molecular level, is the most significant discovery in the history of genetics. Previous researches on DNA included topics ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

This valuable descriptive manuscript builds on prior research showing that the elimination of Origin Recognition Complex (ORC) subunits does not halt DNA replication. The authors obtain solid data ...

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The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

DNA replication is one of the most well-orchestrated cellular processes that needs to proceed in a faithful and timely manner. However, this process is continuously challenged, leading to stalled ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Univ Brest, Ifremer, Biologie et Ecologie des Ecosystèmes Marins Profonds (BEEP), Plouzané, France In my opinion, these discoveries challenge the “classical” models of DNA replication. Archaea are not ...