Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Decades of research has viewed DNA as a sequence-based instruction manual; yet every cell in the body shares the same genes – so where is the language that writes the memory of cell identities?

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein engineering.