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Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
Bayer has filed separate lawsuits against the creators of three COVID-19 vaccines, claiming they violated intellectual ...
This article and associated images are based on a poster originally authored by Divya Vemula and Vasundhra Bhandari and presented at ELRIG Drug Discovery 2025 in affiliation with the National ...
Abstract: Co-optimizing mRNA sequences for both codon optimality and secondary structure is crucial for producing stable and efficacious mRNA therapeutics. Codon optimization, which adjusts nucleotide ...
Fungal pathogens rely on G protein–coupled receptors (GPCRs) to sense environmental cues and coordinate host infection. By establishing a yeast mating platform for multiplex GPCR–ligand screening, we ...
Background: Colorectal cancer (CRC) has emerged as a growing global health challenge, while immunotherapy, particularly mRNA-based cancer vaccines, has emerged as a promising approach due to its ...
Users are more prepared to buy than ever before when they arrive at your site from an answer engine. The answer engine optimization industry has been infected by a terrible disease of terms that don’t ...
Microbial systems offer distinct advantages in protein expression, saving costs and time, and offering well-characterized host genetics and ease of scale-up. 2 However, challenges remain in process ...
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