To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...

1 Department of Mathematics and Physics, University of Wisconsin-Parkside, Kenosha, WI, USA. 2 Department of Biological Sciences, University of Wisconsin-Parkside, Kenosha, WI, USA. Based on the ...

Abstract: Oligo DNA microarrays are fabricated through in-situ chemical synthesis. Contact and fluid dynamics all contribute to this process. To produce high quality oligo DNA microarrays, it is ...

A recent study on DNA microarray technology highlights its essential role in enabling high-throughput analysis of large numbers of genes through arrays of probes integrated on a solid-phase support.

This study provides convincing evidence that homologous recombination can occur in telophase-arrested cells, independently of cohesin subunits Smc 1-3. These findings are valuable as they point to ...

James D. Watson, whose co-discovery of the twisted-ladder structure of DNA in 1953 helped light the long fuse on a revolution in medicine, crimefighting, genealogy and ethics, has died. He was 97. The ...

James Watson, who co-discovered the double-helix structure of DNA in 1953, has died at age 97. Born in Chicago in 1928, Watson made the groundbreaking discovery at just 24 years old alongside British ...

In pro-B cells, VDJ recombination at the immunoglobulin heavy chain locus is impaired. B cell progenitor recombination implies the formation of DNA double strand breaks (DSBs) by the RAG recombinase, ...

You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...