Background: Tetralogy of Fallot (TOF) is one of the most common complex congenital heart diseases, posing a severe threat to infant health. This study aims to investigate the core genes and pathways ...
Abstract: Most pathway analysis methods based on simple nucleotide variations overlook mutations occurring in genes outside the pathway, fail to address mutation heterogeneity with targeted measures, ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Motivated by ...
Abstract: Hypertension is a serious cardiovascular disease that substantially raises morbidity and mortality rates worldwide. People who have high blood pressure have been found to have an increased ...
ACVR2A was downregulated in placental tissue associated with pre-eclampsia. (A) Comparison of the RNA-seq volcano maps of all genes in the placenta of normal control (NC) and patients with ...
Pathway enrichment analysis is indispensable for interpreting omics datasets and generating hypotheses. However, the foundations of enrichment analysis remain elusive to many biologists. Here, we ...
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Green technological innovation is essential for promoting high-quality regional economic growth. The digital economy, characterized by penetration, integration, and sustainability, significantly ...