A new CRISPR-based approach for tuning gene expression up and down allowed identification of how other genes' expression responds to changes of transcription factors.

Introduction We aimed to determine the association between paternal labour migration and the growth of the left-behind ...

Background Annually, 4% of the global population undergoes non-cardiac surgery, with 30% of those patients having at least ...

Objectives to describe the evolution of anxiety during the COVID-19 pandemic in France and to assess whether it differed according to pre-existing alcohol misuse. Design A prospective longitudinal ...

Objective Anxiety affects up to one-third of adults with asthma and is linked to poorer disease outcomes and reduced quality ...

Background Axial spondyloarthritis (axSpA) impairs trunk strength, mobility and cardiorespiratory fitness. Despite exercise being a key treatment, few studies have examined a combined trunk mobility, ...

We estimated CKM syndrome stage prevalence and used directed acyclic graph-informed multivariable generalized linear models to evaluate the association between CKM stages 0-2 and risk of TOI by ICD-10 ...

In microbiome studies, addressing the unique characteristics of sequence data—such as compositionality, zero inflation, overdispersion, high dimensionality, and non-normality—is crucial for accurate ...

Abstract: For a relatively small labeled dataset from high-dimensional generalized linear models with block-wise missing covariates and a large unlabeled dataset, we utilize a model-assisted approach ...

1 Centre for Global Change, Sol Plaatje University, Kimberley, South Africa 2 Department of Computer Science and Information Technology, Faculty of Natural and Applied Sciences, Sol Plaatje University ...