High-performance liquid chromatography (HPLC) or ultra-high-performance liquid chromatography (UHPLC) serves as the front end of the analysis, reducing sample complexity before mass detection.

The LC-MS/MS workflow provides precise quantification of rAAV9 capsid proteins, overcoming limitations of SDS-PAGE and ELISA in stoichiometry determination. Isotopically labeled peptides in LC-MS/MS ...

Sample preparation plays a crucial role in bioanalytical analysis involving chromatography. Insufficient sample preparation, such as skipping protein precipitation, phospholipid removal (PLR), ...

Discover how advanced LC-MS/MS can deliver robust, low-maintenance performance for food contaminant testing, enabling faster results, high throughput and reliable accuracy across challenging food ...

Microsoft is betting big on AI. Starting with integrating Bing with ChatGPT, it has implemented AI capabilities in its products. Microsoft Designer is a new product from Microsoft with AI capabilities ...

Abstract: This tutorial will go through the fundamentals of LC oscillator and LC VCO design, such as basic phase-noise theory, design for low power, low phase noise and, large tuning range (including ...

Despite the many benefits MS offer for CQAs monitoring, non-MS LC based analytics remain the industrial standard for PAT applications in biologics manufacturing as MS is often perceived to be too ...

Liquid chromatography−tandem mass spectrometry is one of the most sensitive and reliable techniques in the quantitative bioanalysis of small molecules, but it is not free of challenges and traps. This ...

ABSTRACT: The study investigated the occurrence of explosive compounds at four demining sites in Amuru District, Northern Uganda. The concentrations of explosive compounds octahydro-1,3,5,7-tetranitro ...