Background: Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, with limited efficacy of current therapies in advanced cases. As a key risk factor for HCC, liver ...

Research led by the SickKids Research Institute in Toronto and the University of Pennsylvania, has found that immune-related ...

Explore how stressors during pregnancy influence foetal brain development and the impact on future neurodevelopmental ...

Abstract: Spatial transcriptomics (ST) are emerging technologies that reveal spatial distributions of gene expressions within tissues, serving as important ways to uncover biological insights. However ...

Maternal gut–immune stress shapes fetal brain development differently in males and females, revealing sex-specific pathways ...

Abstract: Spatial transcriptomics has emerged as a transformative technology for mapping gene expression within tissue contexts, offering unprecedented insights into disease mechanisms. However, ...

The maternal microbiome and immune system have both independent and synergistic effects on fetal brain health - changes in ...

The maternal microbiome and immune system have both independent and synergistic effects on fetal brain health - changes in the mother's immune system ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...