ABSTRACT: Lung cancer ranks at the top in both incidence and mortality among malignant tumors worldwide. In China, the incidence and mortality of lung cancer are the highest among all malignant tumors ...

Hirschsprung’s disease (HSCR) is characterized by congenital absence of ganglion cells in the gastrointestinal tract, which leads to impaired defecation, constipation and intestinal obstruction. The ...

Disparities in estrogen receptor (ER), progesterone receptor, human epidermal growth factor receptor 2 (HER2), and Ki67 proliferation indices facilitate the categorization of breast cancer into four ...

Abstract: MicroRNAs (miRNAs) are reported to play essential roles in cancer initiation and progression and microarray technologies are intensively applied to study the miRNA expression profile in ...

Building on on the observation of an increase in miR-182-5p in diabetic patients, the authors investigated the role of miR-182-5p and its target gene LRP6 in dysregulated glucose tolerance and fatty ...

OBJECTIVES: The aim of this study was to compare the expression levels of serum miRNAs in diabetic retinopathy and type 2 diabetes mellitus. METHODS: Serum miRNA expression profiles from diabetic ...

We and others have found inconsistencies in miRNA expression levels between different array platforms, highlighting the current technical challenges and limitations of miRNA studies. A recent, ...

Abstract: In recent years, microRNAs (miRNAs) play critical roles in many important biological processes, and are therefore studied as key regulators of gene expression involved in complex diseases.