Protein serine/threonine kinases (STKs) regulate critical signaling pathways involved in cell growth, proliferation, metabolism, and apoptosis. Aberrant kinase activity is implicated in diverse human ...

Abstract: Traditional molecular docking approaches often overlook water molecules or treat them as rigid entities, which compromises docking accuracy and fails to capture realistic biomolecular ...

Overview Antimicrobial resistance represents a critical global health challenge. Among resistant pathogens, Klebsiella pneumoniae has emerged as a significant concern due to its ability to produce New ...

Introduction: Among diverse chemical profile of Cannabis sativa L., over 100 phytocannabinoids have been identified. The major cannabinoids Δ-9-THC and CBD are well-studied, with approved palliative ...

Department of General Biology, Federal University of Viçosa, Viçosa 36570-000, MG, Brazil Department of Animal Biology, Federal University of Viçosa, Viçosa 36570-000, MG, Brazil ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Cirrhosis, characterized by liver fibrosis and structural remodeling, is a leading ...

Educators are increasingly using generative A.I. in their own work, even as they express profound hesitation about the ethics of student use. By Dana Goldstein As artificial intelligence makes its way ...

C-T-P, compound-target-pathway; DL, drug-likeness; GO, gene ontology; OB, oral bioavailability; PPI, protein-protein interaction; RA, rheumatoid arthritis; TCMSP, Traditional Chinese Medicine Systems ...