CTx001 is an investigational AAV-based gene therapy designed to modulate multiple pathways of the complement system Opti-GAIN is a first-in-human trial to evaluate the safety, tolerability, and ...

One of the fundamental purposes of biotherapeutic research, development, and production is to assure the safety and efficacy of medicinal products in clinical settings. Analytical tools are critical ...

Abstract: In this paper, the decomposition projective method based on orthogonal complement space is presented, which can refine and accelerate the original decomposition projective method when ...

The complement cascade was identified over 100 years ago, yet investigation of its role in pregnancy remains an area of intense research. Complement inhibitors at the maternal-fetal interface prevent ...

In 2014, specific recommendations for complement nomenclature were presented by the complement field. There remained some unresolved designations and new areas of ambiguity, and here we propose ...