Co-founded by Jennifer Doudna and Fyodor Urnov, the company intends to simultaneously develop many gene editing treatments for rare conditions by using the agency’s “plausible mechanism” pathway.

Researchers discovered that tanning beds cause widespread, mutation-laden DNA damage across almost all skin, explaining the sharply increased melanoma risk. Single-cell genomic analysis revealed ...

ABSTRACT: Gastric cancer (GC) is a major cause of cancer mortality. GC studies that aim to identify relevant oncogenes and tumor suppressor genes (TSGs) are essential for devising effective new ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...

A fundamental characteristic of gene mutations is the permanent alteration of the DNA sequence, including point mutations, deletions, inversions, and translocations. Among these, DNA point mutation ...

The utility will currently generate the same input types for queries as mutations. Example of generated input type and its usage in queries and mutations: input AirportInput { _id: ID type: String ...

Bottom line: Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic alterations that can be associated with resistance to KRAS G12C ...

Individuals with TET2 mutations display diverse progression and outcomes in hematopoietic diseases, highlighting the distinct pathological effects of different TET2 variants. This study explores the ...

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others ...