Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

Post-translational modifications (PTMs) represent a pivotal regulatory mechanism in cellular processes, wherein the addition or removal of specific functional groups to amino acid residues dynamically ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States Department of Biochemistry and Biophysics, University of North Carolina ...

Chronic kidney disease (CKD) involves intricate pathological mechanisms that currently lack definitive therapeutic interventions to halt disease progression. Increasing evidence suggests that ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

Abstract: O-linked glycosylation is a complex form of posttranslational modification in human proteins that plays a crucial regulatory role in a wide range of cell types. It is intimately involved in ...

ABSTRACT: Papillomaviruses have the ability to induce infected squamous epithelial cells to form tumors, some of which can progress to malignancies. They are circular double-stranded DNA viruses with ...

Respiratory infections, pink eye, or an upset stomach may seem like unrelated, mild inconveniences, but all of these ailments share one root cause: adenovirus infection. Many of us will encounter some ...

Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...