A Scripps team has adapted advanced imaging and computation to measure cell membrane thickness inside intact animal and yeast ...
Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...
Protein arginylation is an evolutionarily conserved post‐translational modification whereby arginine is covalently attached to specific residues on target proteins. Mediated principally by the enzyme ...
Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, ...
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Ageing slows brain protein clearance and shifts synaptic waste to microglia
By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...
After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...
Researchers have identified a key molecular interaction that accelerates Parkinson’s disease by damaging the brain’s energy ...
Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have found that a key ...
The involvement of glial cells in Alzheimer's disease (AD) has been mostly viewed as a secondary adaptive response to ...
Many people still don’t understand how protein works, why it matters or the best ways to get enough of it in their diet. Here ...
Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...
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