Recent progress in single-cell RNA sequencing has led to mechanistic and clinically actionable insight into genetic heterogeneity and tumor progression via transcriptome profiling at single-cell level ...

yorzoi is a deep neural network that predicts RNA-seq coverage from DNA sequence in Yeast (S. Cerevisiae). It is available via PyPI and Huggingface (see installation). Yorzoi is available at yorzoi.eu ...

Researchers from Stockholm University have—for the first time ever—managed to successfully isolate and sequence RNA molecules from Ice Age woolly mammoths. These RNA sequences are the oldest ever ...

A woolly mammoth that was frozen in the Siberian permafrost for nearly 40,000 years has yielded the world’s oldest RNA. The specimen, found in 2010 and nicknamed Yuka, is regarded as the ...

Abstract: Recently, with the growth of the required data size for emerging applications (e.g., graph processing and machine learning), the von Neumann bottleneck has become a main problem for ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Traditional PCR systems require users to set a specified number of cycles according to the assay and the input amount. As a result, input material must be quantified, and samples of varying inputs ...

Single-nuclei RNA sequencing (snRNA-seq) has revolutionized our understanding of gene expression heterogeneity in complex tissues like the brain. The Human Protein Atlas provides comprehensive ...

Chemists at University College London have shown how two of biology's most fundamental ingredients, RNA (ribonucleic acid) and amino acids, could have spontaneously joined together at the origin of ...

This study presents a useful finding for the ferroptosis-mediated tumor microenvironment (TME) in triple-negative breast cancer (TNBC) using public single-cell RNA sequencing (scRNA-seq) and bulk RNA ...