T-cell engagers are antibody-based therapeutics that can reprogram T cells for antigen-specific elimination of target cells.

Chemotherapy reshapes gut bacteria in ways that send powerful signals throughout the body. These signals reprogram immune cells, making organs like the liver more resistant to metastatic cancer.

Trained immunity enhances innate immune responses, yet a Western lifestyle may lead to maladaptive trained immunity and drive non-communicable diseases.

The conversation around longevity is shifting. For decades, the goal was simple: live longer. But as medicine advances and ...

The tumor microenvironment (TME) is a metabolically dynamic niche where cancer cells and immune cells interact to influence tumor progression and immune ...

T cells are central mediators of autoimmune disease pathogenesis, yet their functional states are not defined solely by antigen recognition or canonical ...

The government is using sickle cell treatments to test a new strategy: paying only if the therapies benefit patients. With ...

Researchers have uncovered a stealthy way pancreatic cancer disarms the immune system, using tiny molecular messengers to ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the University of Massachusetts Amherst, could have applications beyond ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...

New insights into a sophisticated process that protects sperm cells has revealed a mechanism, similar to an immune system, thwarts genetic chaos during the earliest stages of their development.

Explore the potential of bacteriophages as a breakthrough therapy against bacterial infections amidst rising antibiotic ...