Advancements in AI, multi-omics, and genome editing are transforming life sciences and biotechnology, addressing new ...

Sensorineural hearing loss (SNHL) is a highly prevalent sensory disorder globally, affecting over 1.5 billion people, with a ...

Peer-reviewed discovery platform and data in PNAS show that single transcription factor modulation reverses aging-associated gene expression and restores healthy cellular and tissue function in models ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

The preprint is available here. DeepSpot2Cell predicts virtual single-cell spatial transcriptomics as follows: (1) During training, the model takes as input (i) the cropped cell tile defined by the ...

Background Most patients with biliary tract cancer (BTC) do not derive durable clinical benefit (DCB) from immune checkpoint inhibitors (ICIs), underscoring the urgent need for predictive biomarkers.

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Single-cell RNA sequencing (scRNA-seq) has emerged as an advanced biological technology capable of resolving the complexity of cancer landscapes at single-cell resolution. Spatial transcriptomics(ST), ...

Unlike animals, plants are sessile organisms that must adapt to localized and fluctuating environmental stimuli, including abiotic and biotic stresses. While animals use mobile immune cells to ...

The link between lymph node (LN) function and atherosclerosis is unclear, especially at the single‐cell level. This study explores the relationship between pericarotid LNs and plaque stability using ...