纵观整项研究，我们不仅看到了FOCAS这一强大工具的威力，更看到了它所揭示的生物学复杂性。过去针对m6A的抗癌策略往往类似于“地毯式轰炸”（如全局抑制METTL3或FTO），虽然有效，但伴随着破坏管家功能的风险。

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...

Transcriptome-based NGS outperforms traditional viral testing with superior sensitivity, detecting viruses including novel ...

12月31日，北京大学以“FOCAS: Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of ...

Advancing RNA therapeutics depends on understanding two critical questions: Where do drug candidates go, and what do they do ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...