◾ARTICLE OF THE WEEK◾ Musculoskeletal disorders are one of the most prevalent and costly disorders globally. A new form of exercise therapy focused on loading and resistance programs that temporarily aggravates a patient’s pain with exercise and movement. This study compared the effects of exercises where pain was allowed/encouraged compared with non-painful exercises on pain, function and disability in patients with chronic musculoskeletal pain. Nine papers with 385 participants were included i